The experiments suggested that cellular aging develops through several stages. The researchers observed changes involving stress resistance first, followed by metabolic changes and eventually epigenetic alterations. Their findings also pointed to differences between males and females, suggesting that the biological process may not unfold identically in everyone.
The Decline May Be Linked To A Major Life Stage
The human data offered another clue that caught the researchers’ attention. Phosphatidylcholine levels appeared to decline rapidly around menopause, a period that is also frequently associated with changes in energy and fatigue.
That connection does not prove that declining phosphatidylcholine causes menopause-related fatigue or other symptoms. It does, however, give scientists another potential biological relationship to investigate as they study why cellular aging can accelerate at different stages of life.
